Delineation of robertsonian translocations in man by means of chromosome banding

✍ Scribed by Fontaine S. Hill; Robert L. Summitt

• Book ID: 104782315
• Publisher: Springer
• Year: 1977
• Tongue: English
• Weight: 536 KB
• Volume: 126
• Category: Article
• ISSN: 0340-6997
• DOI: 10.1007/bf00477046

✦ Synopsis

Robertsonian translocations from thirteen unrelated individuals were studied by G, Q and C banding, and by autoradiography. Each of three D-D translocations involved chromosomes 13 and 14, all four D-G translocations involved chromosomes 14 and 21, and five of six G-G translocations involved two chromsomes 21 while the sixth involved 21 and 22. Two centromeres were noted in a single 21-21 translocation chromosome by C banding. Autoradiogrpahy was much less useful in identifying the chromosomes involved in the thirteen translocations. G and Q banding were consistently accurate.