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Delineation of a DNA Recognition Element for the Vitamin D3 Receptor by Binding Site Selection

✍ Scribed by R. Perezfernandez; V. Arce; L.P. Freedman


Book ID
115572860
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
595 KB
Volume
192
Category
Article
ISSN
0006-291X

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## Abstract Our recent studies have shown that the vitamin D analog Ro‐26‐9228 restores bone mineral density without inducing hypercalcemia in osteopenic rats. Our ex vivo experiments demonstrated that the analog upregulated gene expression in trabecular bone but not in the duodenum of female rats.