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Delineating the sites and progression of in vivo atrophy in multiple system atrophy using fluid-registered MRI

✍ Scribed by Jonathan M. Schott; Jessica E. Simon; Nick C. Fox; Andrew P. King; M. Nadeem Khan; Lisa Cipolotti; Dominic C. Paviour; John M. Stevens; Martin N. Rossor


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
263 KB
Volume
18
Category
Article
ISSN
0885-3185

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✦ Synopsis


Abstract

We describe the pattern and progression of atrophy delineated using fluid registration of serial magnetic resonance imaging scans in a case of multiple system atrophy (MSA). The in vivo findings were consistent with those found at postmortem, including significant supratentorial atrophy concurrent with an unusual degree of cognitive impairment for MSA. © 2003 Movement Disorder Society


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## Abstract To investigate the diagnostic value of brain magnetic resonance image (MRI) and ^18^F‐fluorodeoxyglucose positron emission tomography (^18^F‐FDG PET) in the differentiation of multiple system atrophy (MSA) from Parkinson's disease (PD). Thirty‐five patients with MSA (23 MSA‐P and 12 MSA