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Delineating common molecular mechanisms in Alzheimer's and prion diseases

✍ Scribed by Kevin J. Barnham; Roberto Cappai; Konrad Beyreuther; Colin L. Masters; Andrew F. Hill


Book ID
113931299
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
413 KB
Volume
31
Category
Article
ISSN
0968-0004

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## Abstract Alzheimer's disease (AD) and prion disease are characterized neuropathologically by extracellular deposits of Aβ and PrP amyloid fibrils, respectively. In both disorders, these cerebral amyloid deposits are co‐localized with a broad variety of inflammation‐related proteins (complement f