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Deletions of Chromosomes 9 and 8p in Histologically Normal Urothelium of Patients with Bladder Cancer

✍ Scribed by Robert Stoehr; Sabrina Zietz; Maximilian Burger; Thomas Filbeck; Stefan Denzinger; Ellen C. Obermann; Christine Hammerschmied; Wolf F. Wieland; Ruth Knuechel; Arndt Hartmann

Book ID
113608728
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
182 KB
Volume
47
Category
Article
ISSN
0302-2838

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Human bladder cancers and normal bladder
Human bladder cancers and normal bladder mucosa present the same hot spot of heterozygous chromosome-9 deletion
✍ Eric Baud; Pierre Catilina; Jean-Paul Boiteux; Yves-Jean Bignon πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 92 KB

Loss of heterozygosity (LOH) on chromosome 9 is the most frequent genetic alteration in bladder cancer identified to date, suggesting the presence of key gene(s) for this pathology. In this study, we examined 44 bladder tumors and 21 normal bladder samples for LOH on both arms of chromosome 9. Sixte