๐”– Bobbio Scriptorium
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DELETION STATUS AND INTELLECTUAL IMPAIRMENT IN DUCHENNE MUSCULAR DYSTROPHY

โœ Scribed by K. M. D. Bushby; R. Appleton; L. V. B. Anderson; J. L. Welch; P. Kelly; D. Gardner-Medwin


Book ID
115266496
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
719 KB
Volume
37
Category
Article
ISSN
0012-1622

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๐Ÿ“œ SIMILAR VOLUMES


Theoretical expectations for deletional
โœ Grimm, Tiemo ;Danieli, Gian A. ;Muller, Clemens R. ;Neri, Giovanni ;Reynolds, Ja ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 327 KB ๐Ÿ‘ 1 views

## To the Editor: In a population, when equilibrium between mutation and selection is reached, a fraction (x) of individuals affected by an X-linked recessive lethal disorder is due to new mutations [Haldane, 19351. Being p, the mutation rate in female germ cells, and v, the mutation rate in male

Theoretical expectations for deletional
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The letter by on the theoretical expectations for deletional mutations in Duchenne muscular dystrophy (DMD) is very misleading. The authors base al1 of their arguments and calculations on the hypothesis that, in DMD, deletions occur exclusively or aimost exclusively by homologous recombination, and