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Deletion of the intracellular domain of coxsackie and adenovirus receptor (CAR) enhances the expression of itself and boosts the efficiency of current adenovirus-mediated gene therapy in ovarian cancer cell lines in vitro

โœ Scribed by Beibei Wang; Gang Chen; Jianfeng Zhou; Peng Wu; Danfeng Luo; Xiaoyuan Huang; Tao Zhu; Zhiqiang Han; Gang Xu; Shixuan Wang; Yunping Lu; Ding Ma


Book ID
116334268
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
414 KB
Volume
248
Category
Article
ISSN
0304-3835

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## Abstract ## Background Hybrid adenoโ€retroviral vector systems utilize the high efficiency of adenovirus transduction to direct the __in situ__ production of retroviral progeny. In this study, we show that a singleโ€step transduction of glioma cells with transโ€complementing hybrid adenoโ€retrovira