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Deletion of the C-Terminal Domain of Apolipoprotein A-I Impairs Cell Surface Binding and Lipid Efflux in Macrophage †

✍ Scribed by Burgess, Jim W.; Frank, Philippe G.; Franklin, Vivian; Liang, Ping; McManus, Dan C.; Desforges, Marc; Rassart, Eric; Marcel, Yves L.


Book ID
127030345
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
127 KB
Volume
38
Category
Article
ISSN
0006-2960

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## Abstract Although the N‐terminal region in human apolipoprotein (apo) A‐I is thought to stabilize the lipid‐free structure of the protein, its role in lipid binding is unknown. Using synthetic fragment peptides, we examined the lipid‐binding properties of the first 43 residues (1–43) of apoA‐I i