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Deletion of the Adenoviral E1b-19kD Gene Enhances Tumor Cell Killing of a Replicating Adenoviral Vector

โœ Scribed by Sauthoff, Harald; Heitner, Sheila; Rom, William N.; Hay, John G.


Book ID
118057457
Publisher
Mary Ann Liebert
Year
2000
Tongue
English
Weight
626 KB
Volume
11
Category
Article
ISSN
1043-0342

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It is now well documented that apoptosis represents the prevalent mode of death in lymphoid cultures and occurs spontaneously in late-exponential phase of batch cultures following nutrient exhaustion. In an attempt to enhance the cell survival of these cell lines, we have initially engineered nonpro