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Deletion of mitochondrial DNA in patients with combined features of kearns-sayre and MELAS syndromes

✍ Scribed by Dr Mary L. Zupanc; Carlos T. Moraes; Sara Shanske; Craig B. Langman; Emma Ciafaloni; Salvatore DiMauro


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
477 KB
Volume
29
Category
Article
ISSN
0364-5134

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A cytogenetically visible interstitial deletion of chromosome band 10q23 was found in a 6-year-old boy with mental retardation, dysmorphic features, and juvenile polyposis coli. In order to map this patient's deletion physically, we performed fluorescence in situ hybridization by using yeast artific