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Deletion of Chromosome 1, But Not Mutation of MEN-1, Predicts Prognosis in Sporadic Pancreatic Endocrine Tumors

โœ Scribed by Sydney S. Guo; Alan Y. Wu; Mark P. Sawicki


Book ID
105978083
Publisher
Springer
Year
2002
Tongue
English
Weight
87 KB
Volume
26
Category
Article
ISSN
0364-2313

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## Abstract Pancreatic endocrine tumors (PETs) occur in association with multiple endocrine neoplasia type 1 (MEN1) and von Hippelโ€Lindau (VHL) syndromes caused by germline alterations in __MEN1__ and __VHL__, respectively. It is thus expected that these genes will also be altered in a proportion o