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Deletion of 17p13 and LIS1 Gene Mutation in Isolated Lissencephaly Sequence

✍ Scribed by Renata C. Elias; Marcial F. Galera; Beatriz Schnabel; Marcelo R.S. Briones; Maria L. Borri; Monica Lipay; Gianna Carvalheira; Decio Brunoni; Maria I. Melaragno


Book ID
116824934
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
198 KB
Volume
35
Category
Article
ISSN
0887-8994

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Clinical and molecular basis of classica
✍ Carlos Cardoso; Richard J. Leventer; James J. Dowling; Heather L. Ward; June Chu πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 516 KB

Classical lissencephaly (LIS) and subcortical band heterotopia (SBH) are related cortical malformations secondary to abnormal migration of neurons during early brain development. Approximately 60% of patients with classical LIS, and one patient with atypical SBH have been found to have deletions or