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Deletion of 11q23 is a highly specific nonrandom secondary genetic abnormality of ETV6/RUNX1-rearranged childhood acute lymphoblastic leukemia

✍ Scribed by Attarbaschi, A; Mann, G; Strehl, S; König, M; Steiner, M; Jeitler, V; Lion, Th; Dworzak, M N; Gadner, H; Haas, O A

Book ID: 110057023
Publisher: Nature Publishing Group
Year: 2007
Tongue: English
Weight: 88 KB
Volume: 21
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2404507

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Deletion of 11q23 is a highly specific n

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Near-tetraploidy in childhood B-cell pre

Near-tetraploidy in childhood B-cell precursor acute lymphoblastic leukemia is a highly specific feature of ETV6/RUNX1-positive leukemic cases

✍ Andishe Attarbaschi; Georg Mann; Margit König; Manuel Steiner; Michael N. Dworza 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB

## Abstract Near‐tetraploidy (82–94 chromosomes) makes up fewer than 1% of childhood acute lymphoblastic leukemia (ALL) cases and has been reportedly associated with a possibly poorer prognosis compared with other ploidy groups. We analyzed 783 patients enrolled in the ALL‐BFM‐Austria 86, ‐90, ‐95,