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Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma

โœ Scribed by Pershouse, Mark A; El-Naggar, Adel K; Hurr, Kenneth; Lin, Huai; Yung, WK Alfred; Steck, Peter A

Book ID
110060496
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
377 KB
Volume
14
Category
Article
ISSN
0950-9232

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Several lines of evidence suggest that the progression of head-and-neck squamous-cell carcinoma (HNSCC) involves inactivation of at least one and possibly several tumorsuppressor genes on the long arm of chromosome 13. The fact that neither Rb1 nor BRCA2 appears to be inactivated in the majority of