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Deletion in exon 5 of the SNCA gene and exposure to rotenone leads to oligomerization of α-synuclein and toxicity to PC12 cells

✍ Scribed by Ma, Kai-Li; Song, Lian-Kun; Long, Whitney Annie; Yuan, Yu-He; Zhang, Ying; Song, Xiu-Yun; Niu, Fei; Han, Ning; Chen, Nai-Hong


Book ID
119210812
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
608 KB
Volume
90
Category
Article
ISSN
0361-9230

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The mixed lineage leukemia gene (MLL) was originally identified through its involvement in reciprocal translocations in leukemias. MLL codes for a large multidomain protein and bears homology to the Drosophila developmental control gene trithorax in two small domains in the amino terminal region, th