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Deletion and site-specific mutagenesis of nucleolin's carboxy GAR domain

✍ Scribed by Gregory J. Pellar; Patrick J. DiMario


Book ID
106089801
Publisher
Springer
Year
2003
Tongue
English
Weight
389 KB
Volume
111
Category
Article
ISSN
0009-5915

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Site-directed mutagenesis of hamster com
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We have previously shown that non-transformed mouse A3 I cells became tumorigenic when they were transfected with hamster C I s cDNA expression plasmid BCMGSNeoCS. In the present study, mutations were introduced into the cDNA at the activation cleavage site, Arg423(AGG) and the active center Ser6 I'