Transcriptional activation of the type I
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Cordula Büttner; Annett Skupin; Ernst Peter Rieber
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Article
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2003
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John Wiley and Sons
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English
⚖ 440 KB
Pneumonitis followed by lung fibrosis is a frequent complication of radiation therapy of chest tumors. A hallmark of these fibrotic lesions is the excessive production and accumulation of extracellular matrix proteins such as type I collagen. In addition to TGF-beta1, IL-4 has been recognized as a p