✦ LIBER ✦
Deletion 9p22-pter and loss of Y as primary chromosome abnormalities in a squamous cell carcinoma of the vocal cord
✍ Scribed by Maria J. Worsham; Michael J. Benninger; Richard J. Zarbo; Thomas E. Carey; Dr. Daniel L. Van Dyke
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 226 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1045-2257
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✦ Synopsis
Abstract
Loss of distal 9p is a common genetic alteration in squamous cell carcinoma of the head and neck. A vocal cord lesion incorporating a carcinoma‐in‐situ and a focus of invasive carcinoma revealed loss of the Y chromosome and a 9p22 rearrangement with loss of 9p22‐pter. Loss of 9p22‐pter appears to be a primary autosomal abnormality in this squamous cell carcinoma. © 1993 Wiley‐Liss, Inc.