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Deletion 12p in de novo acute myeloid leukemia: An association with early progenitor cell

✍ Scribed by L.C. Chan; Y.L. Kwong; H.W. Liu; C.P. Lee; K.W. Lie; A.Y.Y. Chan


Book ID
119105303
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
218 KB
Volume
62
Category
Article
ISSN
0165-4608

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We report on an adult patient with de novo acute myeloid leukemia (AML) with a t(11;22)(q23;q11.2) involving CDCREL1 and MLL genes. Reverse transcriptase (RT)-polymerase chain reaction (PCR) followed by direct sequencing analysis revealed the MLL-CDCREL1 fusion transcript in his leukemic cells. Anal