Based on graft rejection in C57BL/6 and B10.A(4R), but not in B10.A mice, skin graft rejection and delayed-type hypersensitivity (DTH) responses to the male HY antigen were considered to be under the control of the "IBb" gene in the mouse H-2 complex. These two phenomena were re-examined in the B6.C
Delayed-type hypersensitivity responses to H-Y: Characterization and mapping ofIrgenes
β Scribed by F. Y. Liew; E. Simpson
- Publisher
- Springer-Verlag
- Year
- 1980
- Tongue
- English
- Weight
- 870 KB
- Volume
- 11-11
- Category
- Article
- ISSN
- 0093-7711
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## Abstract A putative antiβHβY receptor antiserum (ARA) was raised in C57BL/6 male mice against splenic T lymphocytes from syngeneic females immunized against HβY antigen. When this antiserum is given i.v. to C57BL/6 females it prevents the expression of HβYβspecific delayedβtype hypersensitivity
## Abstract A previous study (__Eur. J. Immunol.__ 1977. __7__: 714) has shown that mice injected intravenously (i.v.) with 1 Γ 10^9^ sheep red blood cells (SRBC) produce cells which suppress delayedβtype hypersensitivity (DTH). These suppressor cells are Ξβpositive, antigenβspecific and act via a