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Delayed Treatment with Nimodipine Improves Cerebral Blood Flow After Complete Cerebral Ischemia in the Dog

✍ Scribed by Newberg, Leslie; Milde, James H.; Michenfelder, John D.


Book ID
109869756
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
396 KB
Volume
6
Category
Article
ISSN
0271-678X

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## Abstract Increasing age decreases the number of new neurons in the dentate gyrus and the subventricular zone (SVZ). Sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, enhances neurogenesis in young rats. The present study tested the hypothesis that sildenafil augments neurogenesis in aged