Delayed treatment with sildenafil enhanc
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Rui Lan Zhang; Zhenggang Zhang; Li Zhang; Ying Wang; Chunling Zhang; Michael Cho
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Article
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2006
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John Wiley and Sons
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English
โ 242 KB
## Abstract Increasing age decreases the number of new neurons in the dentate gyrus and the subventricular zone (SVZ). Sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, enhances neurogenesis in young rats. The present study tested the hypothesis that sildenafil augments neurogenesis in aged