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Delayed reduction of the protein level in the striatum after genetic ablation of the tyrosine hydroxylase gene in the substantia nigra

✍ Scribed by Hiroaki Sakane; Chiho Sumi-Ichinose; Masayo Kojima; Yoshinori Aso; Shin-ichi Muramatsu; Imaharu Nakano; Keiya Ozawa; Takahide Nomura; Ikuko Nagatsu; Toshiharu Nagatsu; Daniel Metzger; Pierre Chambon; Hiroshi Ichinose


Book ID
116775422
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
96 KB
Volume
58
Category
Article
ISSN
0168-0102

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## Abstract Forskolin (FSK) was locally injected into the substantia nigra (SN) of anesthetised rats. The day after injection (24 and 36 hr), tyrosine hydroxylase (TH) activity increased locally in this structure but remained unmodified in the ipsilateral caudate nucleus (CN). The amount of messeng