𝔖 Bobbio Scriptorium
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Delayed radiation-induced bulbar palsy mimicking ALS

✍ Scribed by Susan A. Glenn; Mark A. Ross


Book ID
101256440
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
97 KB
Volume
23
Category
Article
ISSN
0148-639X

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✦ Synopsis


We describe a patient presenting with progressive bulbar dysfunction and spasticity that clinically mimicked amyotrophic lateral sclerosis (ALS). Electromyography, however, showed no evidence of denervation and revealed a rare combination of peripheral and central myokymia. We feel that this pattern of myokymia represented a marker of neural injury from remote radiation therapy. Nervous system disorders resulting from therapeutic radiation are described, and potential pathophysiologic mechanisms underlying myokymia are discussed.