Delayed hypothermia preferentially increases expression of brain-derived neurotrophic factor exon III in rat hippocampus after asphyxial cardiac arrest

Endothelin increases expression of exon

Endothelin increases expression of exon III- and exon IV-containing brain-derived neurotrophic factor transcripts in cultured astrocytes and rat brain

✍ Yutaka Koyama; Kimiko Tsujikawa; Toshio Matsuda; Akemichi Baba 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 441 KB 👁 1 views

The effects of endothelins (ETs) on brain-derived neurotrophic factor (BDNF) production in astrocytes were investigated. ET-1 (100 nM) increased the mRNA level and extracellular release of BDNF in cultured astrocytes. RT-PCR analyses using primer pairs that amplified exon-specific BDNF transcripts r