Delayed hyper-enhancement of myocardium in hypertrophic cardiomyopathy with asymmetrical septal hypertrophy: Comparison with global and regional cardiac MR imaging appearances
✍ Scribed by Yasuo Amano; Morimasa Takayama; Katsuya Takahama; Tatuso Kumazaki
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 453 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
Purpose
To evaluate the relationship between delayed hyper‐enhancement of the myocardium and global and regional cardiac abnormalities in hypertrophic cardiomyopathy (HCM) with asymmetrical septal hypertrophy using magnetic resonance (MR) imaging.
Materials and Methods
Twenty‐three patients with HCM with asymmetrical septal hypertrophy were examined using a 1.5‐T MR unit. Contrast‐enhanced inversion‐recovery gradient‐echo imaging was performed to observe the myocardial damages associated with HCM. Balanced steady‐state free precession imaging was performed to assess regional wall abnormalities and ejection fraction, and black‐blood fast spin‐echo imaging was performed to assess left atrial diameter.
Results
Delayed hyper‐enhancement of the myocardium was primarily observed in the interventricular septal wall. Septal walls with the higher transmural extent of delayed hyper‐enhancement were significantly thicker at end‐diastole and end‐systole (P < 0.05), and tended to show a decreased percentage systolic wall thickening (P = 0.079). There were no differences in theses values between non‐enhancing septal walls and septal walls with the transmural extent < 50%.
Conclusion
The high transmural extent of delayed hyper‐enhancement of the myocardium may reflect the severe myocardial damage associated with the regional hypertrophy and hypokinesia in HCM. J. Magn. Reson. Imaging 2004;20:595–600. © 2004 Wiley‐Liss, Inc.