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Delayed activation of calcium pump during transient increases in cellular Ca2+ concentration and K+ conductance in hyperpolarizing human red cells

✍ Scribed by Ole Scharff; Birthe Foder


Book ID
115727801
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
721 KB
Volume
861
Category
Article
ISSN
0005-2736

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Biphasic rises in cytosolic free Ca2+in
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During exposure to a hypotonic solution (55% osmolarity), cultured human epithelial (Intestine 407) cells exhibit a regulatory volume decrease after osmotic swelling. This process is known to involve parallel activation of volume-regulatory K + and C1-conductances. Biphasic increase in the cytosolic