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Delamanid for Multidrug-Resistant Pulmonary Tuberculosis

✍ Scribed by Gler, Maria Tarcela; Skripconoka, Vija; Sanchez-Garavito, Epifanio; Xiao, Heping; Cabrera-Rivero, Jose L.; Vargas-Vasquez, Dante E.; Gao, Mengqiu; Awad, Mohamed; Park, Seung-Kyu; Shim, Tae Sun; Suh, Gee Young; Danilovits, Manfred; Ogata, Hideo; Kurve, Anu; Chang, Joon; Suzuki, Katsuhiro; Tupasi, Thelma; Koh, Won-Jung; Seaworth, Barbara; Geiter, Lawrence J.; Wells, Charles D.

Book ID: 111878974
Publisher: Massachusetts Medical Society
Year: 2012
Tongue: English
Weight: 693 KB
Volume: 366
Category: Article
ISSN: 0096-6762
DOI: 10.1056/nejmoa1112433

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## Background: Delamanid (opc-67683), a nitro-dihydro-imidazooxazole derivative, is a new antituberculosis medication that inhibits mycolic acid synthesis and has shown potent in vitro and in vivo activity against drug-resistant strains of mycobacterium tuberculosis. ## Methods: In this randomize

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