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Dehydroepiandrosterone Stimulates Neurogenesis in Mouse Embryonal Carcinoma Cell- and Human Embryonic Stem Cell-Derived Neural Progenitors and Induces Dopaminergic Neurons

✍ Scribed by Azizi, Hossein; Mehrjardi, Narges-Zare; Shahbazi, Ebrahim; Hemmesi, Katayoun; Bahmani, Mirza Khalil; Baharvand, Hossein

Book ID
120417597
Publisher
Mary Ann Liebert
Year
2010
Tongue
English
Weight
770 KB
Volume
19
Category
Article
ISSN
1547-3287

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## Abstract A reliable method to induce neural progenitor/stem cells (NPCs) into dopaminergic (DAergic) neurons has not yet been established. As well, the mechanism involved remains to be elucidated. To induce DAergic differentiation from NPCs, a cytokine mixture (C‐Mix) of interleukin (IL)‐1Ξ², IL‐