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Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers

โœ Scribed by Prestrelski, S.J.; Tedeschi, N.; Arakawa, T.; Carpenter, J.F.

Book ID
119409979
Publisher
Biophysical Society
Year
1993
Tongue
English
Weight
983 KB
Volume
65
Category
Article
ISSN
0006-3495

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## Abstract The prediction of changes in protein stability and structure resulting from single amino acid substitutions is both a fundamental test of macromolecular modeling methodology and an important current problem as high throughput sequencing reveals sequence polymorphisms at an increasing ra