Degradome expression profiling in human articular cartilage
✍ Scribed by Tracey E Swingler, Jasmine G Waters, Rosemary K Davidson…
- Book ID
- 120706872
- Publisher
- BioMed Central
- Year
- 2009
- Tongue
- English
- Weight
- 330 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1478-6354
- DOI
- 10.1186/ar2741
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Traumatic injury to a joint can initiate cartilage degradation. Blunt trauma increases matrix damage and decreases proteoglycan synthesis in in vitro models. Few studies have investigated gene expression of articular cartilage (AC) following mechanical loading. Recent advances in microa
## Objective: To assess whether substance p and the corresponding neurokinin 1 (nk1) receptor are expressed in human articular cartilage, and whether these molecules have a role in chondrocyte mechanotransduction. ## Methods: Transgenic studies, immunohistochemistry, western blotting, and reverse