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Degradation of transcription factors, c-Jun and c-Fos, by calpain

✍ Scribed by Syu-ichi Hirai; Hiroshi Kawasaki; Moshe Yaniv; Koichi Suzuki

Book ID: 115924346
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 509 KB
Volume: 287
Category: Article
ISSN: 0014-5793
DOI: 10.1016/0014-5793(91)80015-u

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## Abstract Activating transcription factor 2 (ATF‐2), c‐Fos, and c‐Jun belong to the bZIP family of transcription factors. Promoters of c‐Fos, c‐Jun, cyclin D1, and cyclin A are targets of ATF‐2 in primary mouse chondrocytes. An ATF‐2 expression vector was co‐transfected with either c‐Fos or c‐Jun