Targetting of the N-terminal domain of t
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Christine Giovane; Gilles Travé; Amélie Briones; Yves Lutz; Bohdan Wasylyk; Etie
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Article
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1999
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John Wiley and Sons
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English
⚖ 443 KB
👁 1 views
The E6 protein of cancer-associated human papillomavirus type 16 (HPV16) binds to cellular p53 and promotes its degradation through the ubiquitin pathway. In an attempt to identify the regions of E6 that could be targetted for functional inhibition, we generated monoclonal antibodies to the HPV16 E6