𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Degradation of progesterone by aspergilli-side chain cleaving enzymes

✍ Scribed by Dr. A. H. El-Refai; A. F. Abdel-Fattah; K. A. Ibrahim; L. A. R. Sallam

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
412 KB
Volume
13
Category
Article
ISSN
0233-111X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The transformation properties of different aspergilli were tested. Our strains possess the capacity of degrading of progesterone side chain. Δ^4^‐androstene‐3,17‐dione, testosterone, and testololactone were detected in all cases but produced in different yields. Two strains, namely, Aspergillus niger 214 and A. flavus 181 proved to be the most active transformers. The transformation abilities of these two strains are profoundly affected by composition of the fermentation medium employed. The media containing ill‐defined compounds, e.g. peptone or yeast extract favour the production of enzymes catalyzing the degradation of the progesterone side chain. Various enzymic transformations of progesterone with these two strains were studied by allowing the fermentation to proceed at different time intervals. It was possible to illustrate schemes for such transformation reactions.

📜 SIMILAR VOLUMES

Enzymic side-chain degradation of proges
Enzymic side-chain degradation of progesterone by Penicillium lilacinum
✍ Dr. A. F. Abdel-Fattah; L. A. R. Sallam; M. H. Kinawy; A. H. El-Refai 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB

## Recently have reported the side-chain degradation of progesterone by representatives of the genus Penicillium. The present report concerns further informations on the side-chain degradation of progesterone by Penicillium lilacinum.

The effect of chemical modification of a
The effect of chemical modification of amino acid side-chains on collagen degradation by enzymes
✍ Paul F. Gratzer; J. Paul Santerre; J. Michael Lee 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 423 KB 👁 1 views

## Abstract In this study, the effects of specific chemical modifications of amino acid side‐chains on the __in vitro__ enzyme degradation of type I collagen was studied. Two monofunctional epoxides of different size and chemistry were used to modify lysine and methylglyoxal was used to modify argi

Degradation of steroids by microorganism
Degradation of steroids by microorganisms. XVIII. The reversibility of steroid-l-dehydrogenation during microbial side chain degradation of sterols by Nocardia
✍ R. Komel; H. Groh; Dr. C. Hörhold 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 302 KB

## Abstract The aerobic side chain degradation of sterols often leads to mixtures of 1,4‐diene and 4‐ene compounds. By an additional anaerobic step a practically complete reverse reaction of the steroid‐1‐dehydrogenation occurs yielding only the corresponding 4‐ene compound.

Demonstration of In Situ Oxidative Degra
Demonstration of In Situ Oxidative Degradation of Lignin Side Chains by Two White-rot Fungi Using Analytical Pyrolysis of Methylated Wheat Straw
✍ Susana Camarero; Guido C. Galletti; Angel T. Martínez 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB 👁 2 views

Table 1. Modification of straw composition and weight loss after solid-state fermentation with Pleurotus eryngii and Phanerochaete chrysosporium (degradation of initial lignin, xyland, arabinan and cellulose contents are indicated in parentheses) Control straw P.eryngii a P.chrysosporium b Extractiv