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Degradation of Partially Oxidized Alginate and Its Potential Application for Tissue Engineering

โœ Scribed by Kamal H. Bouhadir; Kuen Yong Lee; Eben Alsberg; Kelly L. Damm; Kenneth W. Anderson; David J. Mooney

Book ID
109386302
Publisher
American Institute of Chemical Engineers
Year
2001
Tongue
English
Weight
147 KB
Volume
17
Category
Article
ISSN
8756-7938

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Degradation of Partially Oxidized Algina
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Alginate has been widely used in a variety of biomedical applications including drug delivery and cell transplantation. However, alginate itself has a very slow degradation rate, and its gels degrade in an uncontrollable manner, releasing high molecular weight strands that may have difficulty being

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## Abstract Hydrogels studied in this investigation, synthesized starting from agarose and Carbomer 974P, were chosen for their potential use in tissue engineering. The strong ability of hydrogels to mimic living tissues should be complemented with optimized degradation time profiles: a critical pr