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Degradation of human articular cartilage by neutrophils in synovial fluid

✍ Scribed by W. Winn Chatham; Richard Swaim; Henry Frohsin Jr; Louis W. Heck; Edward J. Miller; Warren D. Blackburn Jr

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 824 KB
Volume: 36
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780360109

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## Abstract ## Objective Recent published studies have shown that cartilage from ADAMTS‐5–knockout mice, but not ADAMTS‐4– or ADAMTS‐1–knockout mice, is significantly protected from degradation. The present study was undertaken to evaluate the respective roles of these enzymes in human cartilage b