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Degradation of HMG-CoA reductase in rat liver is cholesterol and ubiquitin independent

✍ Scribed by Gene C. Ness; Reed C. Holland


Book ID
116465645
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
142 KB
Volume
579
Category
Article
ISSN
0014-5793

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We have studied the correlation between changes in the lipid composition in chick liver microsomes and the activities of 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA reductase) and acyl-CoA: cholesterol acyltransferase (ACAT) by in vivo and in vitro experiments with 21-day-old chicks. A 5% chol