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Degradation and drug-release studies of a poly(glycolide-co-trimethylene carbonate) copolymer (Maxon)

✍ Scribed by K. Noorsal; M. D. Mantle; L. F. Gladden; R. E. Cameron


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
504 KB
Volume
95
Category
Article
ISSN
0021-8995

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## Abstract Sirolimus‐containing poly(lactide‐__co__‐glycolide) (PLGA) films were prepared by solution casting and removing the residual solvent, 1,4‐dioxane, by liquid and supercritical carbon dioxide (CO~2~) extraction. The effect of lactide:glycolide ratio, stereochemistry of PLGA, and extractio