✦ LIBER ✦

Definition of a physiologic pharmacokinetic model of cutaneous drug distribution using the isolated perfused porcine skin flap

✍ Scribed by Patrick L. Williams; J. Edmond Riviere

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 681 KB
Volume: 78
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600780708

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A physiologically relevant pharmacokinet

A physiologically relevant pharmacokinetic model of xenobiotic percutaneous absorption utilizing the isolated perfused porcine skin flap

✍ Patrick L. Williams; Michael P. Carver; J. Edmond Riviere 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 780 KB

Pharmacologic modulation of the cutaneou

Pharmacologic modulation of the cutaneous vasculature in the isolated perfused porcine skin flap

✍ Richard A. Rogers; Jim E. Riviere 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 790 KB

A valid equation for the well-stirred pe

A valid equation for the well-stirred perfusion limited physiologically based pharmacokinetic model that consistently accounts for the blood–tissue drug distribution in the organ and the corresponding valid equation for the steady state volume of distribution

✍ Leonid M. Berezhkovskiy 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB 👁 1 views

A consistent account of the assumptions of the well-stirred perfusion limited model leads to the equation for the organ tissue that does not coincide with that often presented in books and papers. The difference in pharmacokinetic profiles calculated by the valid and the commonly used equations coul