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Defining the structure of membrane-bound human blood coagulation factor Va

✍ Scribed by S. STOILOVA-MCPHIE; C. D. J. PARMENTER; K. SEGERS; B. O. VILLOUTREIX; G. A. F. NICOLAES

Book ID
109152373
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
449 KB
Volume
6
Category
Article
ISSN
1538-7933

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Human protein C is a vitamin K-dependent plasma protein that serves as a feedback down-regulator of the coagulation cascade by specifically degrading the protein cofactors VIIIa and Va. The protein C precursor consists of the following domains: leader peptide, "gla" region, two epidermal growth fact