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Defining the minimum size of a hydrophobic cluster in two-stranded α-helical coiled-coils: Effects on protein stability

✍ Scribed by Stephen M. Lu; Robert S. Hodges


Book ID
111752230
Publisher
Cold Spring Harbor Laboratory Press
Year
2004
Tongue
English
Weight
300 KB
Volume
13
Category
Article
ISSN
0961-8368

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✍ Wayne D. Kohn; Cyril M. Kay; Robert S Hodges 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB 👁 2 views

The effects on protein stability of negatively charged Glu side chains at different positions along the length of the a-helix were investigated in the two-stranded a-helical coiled-coil. A native coiled-coil has been designed which consists of two identical 35 residue polypeptide chains with a hepta