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Defining the function of β-catenin tyrosine phosphorylation in cadherin-mediated cell–cell adhesion

✍ Scribed by Junji Tominaga; Yoshitaka Fukunaga; Edgardo Abelardo; Akira Nagafuchi


Book ID
108731986
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
305 KB
Volume
13
Category
Article
ISSN
1356-9597

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β‐catenin plays an essential role in cells, not only as a cadherin‐associated complex, but also as a signaling molecule in the nucleus. Tyrosine phosphorylation of β‐catenin has been shown to correlate with tumorigenesis, cell migration, and developmental processes. However, its exact effects on dow