Defining genetic predisposition to multifactorial disease: Application of a two-tiered association approach to schizophrenia

Novel association approach for determini

Novel association approach for determining the genetic predisposition to schizophrenia: Case-control resource and testing of a candidate gene

✍ Sobell, Janet L. ;Heston, Leonard L. ;Sommer, Steve S. 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 1008 KB

additional candidate genes are tested in this case-control resource, adjustment for multiple comparisons will become crucial in order to reduce the chance of false positive findings. The ascertainment of auxillary groups of cases and controls with sequential hypothesis testing in these groups offer