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Defining features of protective CD4 T cell responses to Mycobacterium tuberculosis

✍ Scribed by Sakai, Shunsuke; Mayer-Barber, Katrin D; Barber, Daniel L


Book ID
125856623
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
417 KB
Volume
29
Category
Article
ISSN
0952-7915

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## Abstract Definition of protective immunity induced by effective vaccines is important for the design of new pathogen control strategies. Inactivation of the PhoP response‐regulator in __Mycobacterium tuberculosis__ results in a highly attenuated strain that demonstrates impressive protective eff