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Defining cancer risks for BRCA germline mutation carriers: implications for surgical prophylaxis

✍ Scribed by Beth Y. Karlan

Book ID
113959131
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
70 KB
Volume
92
Category
Article
ISSN
0090-8258

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## Abstract There is conflicting evidence as to whether individuals who are heterozygous for germ‐line __BRCA1__ or __BRCA2__ mutations have an altered phenotypic cellular response to irradiation. To investigate this, chromosome breakage and apoptotic response were measured after irradiation in per