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Deficit of uridine diphosphate galactose in galactosaemia

✍ Scribed by W. G. Ng; Y. K. Xu; F. R. Kaufman; G. N. Donnell


Publisher
Springer
Year
1989
Tongue
English
Weight
744 KB
Volume
12
Category
Article
ISSN
0141-8955

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✍ Wayne D. Klohs; James R. Wilson; Milton M. Weiser; Oscar Frankfurt; Ralph J. Ber πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 582 KB

## Abstract UDPgalactose inhibits the growth of mouse leukemic L1210 cells. In calf serum supplemented Dulbecco's medium (CS‐DMEM), 1.2 mM UDPgalactose (UDPgal) inhibited cell growth by 50% (IC~50~), and 5 mM UDPgalactose inhibited cell growth by 92%. Other nucleotide sugars as well as galactose, g