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Deficient sustained attention to response task and P300 characteristics in early Huntington’s disease

✍ Scribed by Hart, E. P.; Dumas, E. M.; Reijntjes, R. H. A. M.; Hiele, K.; Bogaard, S. J. A.; Middelkoop, H. A. M.; Roos, R. A. C.; Dijk, J. G.

Book ID: 113040423
Publisher: Springer
Year: 2011
Tongue: English
Weight: 281 KB
Volume: 259
Category: Article
ISSN: 0340-5354
DOI: 10.1007/s00415-011-6334-0

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## Abstract Striatal neurons in symptomatic Huntington's disease (HD) transgenic mice are resistant to a variety of toxic insults, including quinolinic acid (QA), kainic acid and 3‐nitropropionic acid. The basis for this resistance is currently unknown. To investigate the possibility that the immed