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Deficient induction of sulfobromophthalein conjugating activity by phenobarbital in hamster liver

✍ Scribed by Armelle Foliot; Dominique Touchard; Anne Myara; François Trivin; Maryline Chauffert

Book ID
115779870
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
449 KB
Volume
36
Category
Article
ISSN
0006-2952

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To determine whether phenobarbital affects hepatocellular bilirubinlsulfobromophthalein uptake mechanism, we administered it to male Sprague-Dawley rats, body weight 175 f 25 g m , at doses of 1 to 75 mg/kg body wtiday for 7 days. Control rats were given an equivalent volume of physiological saline