Deficiency of antibody response to hypervariable region of hepatitis C virus in patients with chronic hepatitis C
β Scribed by Kentaro Yoshioka; Yasuyuki Higashi; Kazuma Tanaka; Toshiyuki Aiyama; Masahiro Takayanagi; Masahiro Takayanagi; Akihiko Okumura; Kazuo Iwata; Yoshiyuki Nagai; Shinichi Kakumu
- Book ID
- 118567433
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 1016 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0168-8278
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π SIMILAR VOLUMES
We assessed the correlation between the positivity for serum IgM antibody to hepatitis C virus and the activity of liver disease in patients with chronic hepatitis C virus infection. Serum samples were taken from 10 antibody to hepatitis C virus-positive asymptomatic patients with normal serum ALT l
The hypervariable domain (HVRI) within the Nterminus of the E2 protein of hepatitis C virus (HCV) is known to be variable antigenically during the course of persistent infection. The aim of the study was to detect B-cell epitopes in HVRI responsible for neutralizing HCV. The B-cell epitopes were ana