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Deferoxamine inhibits methyl mercury-induced increases in reactive oxygen species formation in rat brain

โœ Scribed by Carl P. LeBel; Syed F. Ali; Stephen C. Bondy


Book ID
113207827
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
632 KB
Volume
112
Category
Article
ISSN
0041-008X

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## Abstract Metals are known to induce the formation of reactive oxygen species (ROS) that initiate oxidative stress, an important mechanism of cell injury. The brain is particularly sensitive to oxidative attack because of its high level of unsaturated lipids and high rate of oxidative metabolism.